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Spyre Therapeutics Inc (SYRE)

Spyre Therapeutics Inc (SYRE)
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Fundamentals

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  • Market Capitalization, $K 6,085,818
  • Shares Outstanding, K 86,841
  • Annual Sales, $ 0 K
  • Annual Income, $ -155,200 K
  • EBIT $ -202 M
  • EBITDA $ -213 M
  • 60-Month Beta 3.12
  • Price/Sales N/A
  • Price/Cash Flow N/A
  • Price/Book 12.76

Options Overview Details

View History
  • Implied Volatility 69.98% (+0.55%)
  • Historical Volatility 79.46%
  • IV Percentile 1%
  • IV Rank 6.16%
  • IV High 222.63% on 09/16/25
  • IV Low 59.96% on 08/18/25
  • Expected Move (DTE 30) 9.43 (13.79%)
  • Put/Call Vol Ratio 999.99
  • Today's Volume 7
  • Volume Avg (30-Day) 251
  • Put/Call OI Ratio 0.96
  • Today's Open Interest 2,147
  • Open Int (30-Day) 8,471
  • Expected Range 58.93 to 77.79

Analyst Rating / Earnings Estimates

Current Rating
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Strong Buy
Based on 18 analysts offering recommendations.
Earnings Estimates - Current Qtr 06/30/26
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  • Average Estimate $-0.70
  • Number of Estimates 6
  • High Estimate $-0.59
  • Low Estimate $-0.80
  • Prior Year $-0.49
  • Growth Rate Est. (year over year) -42.86%

Price Performance

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Period Period Low Period High Performance
1-Month
66.96 +0.22%
on 05/19/26
78.80 -14.84%
on 05/11/26
-5.90 (-8.08%)
since 04/17/26
3-Month
37.81 +77.49%
on 02/20/26
78.80 -14.84%
on 05/11/26
+29.30 (+77.49%)
since 02/19/26
52-Week
13.93 +381.75%
on 06/17/25
78.80 -14.84%
on 05/11/26
+52.23 (+350.99%)
since 05/19/25

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 80% Buy with a Average short term outlook on maintaining the current direction.

Long term indicators fully support a continuation of the trend.

Relative Strength just crossed below 50%. The market is indicating support for a bearish trend.

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Business Summary

Spyre Therapeutics is a biotechnology company which aims to create inflammatory bowel disease products by combining antibody engineering, rational therapeutic combinations and precision medicine approaches for patient selection. Spyre Therapeutics, formerly known as Aeglea BioTherapeutics Inc., is based...

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Key Turning Points

3rd Resistance Point 80.79
2nd Resistance Point 78.22
1st Resistance Point 74.15
Last Price 66.04
1st Support Level 67.51
2nd Support Level 64.94
3rd Support Level 60.87

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52-Week High 78.80
Last Price 66.04
Fibonacci 61.8% 54.02
Fibonacci 50% 46.37
Fibonacci 38.2% 38.71
52-Week Low 13.93

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