Ionis Pharmaceuticals (IONS)
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Fiscal Year End Date: 12/31
(Values in U.S. thousands)
| 12-2025 | 12-2024 | 12-2023 | 12-2022 | 12-2021 | |
| Sales | 943,711 | 705,138 | 787,647 | 587,367 | 810,456 |
| Cost of Goods | 15,909 | 11,215 | 9,133 | 14,116 | 10,842 |
| Gross Profit | 927,802 | 693,923 | 778,514 | 573,251 | 799,614 |
| Operating Expenses | 1,310,395 | 1,169,219 | 1,132,377 | 983,558 | 830,642 |
| Operating Income | -381,684 | -475,081 | -353,730 | -410,191 | -30,186 |
| Interest Expense | 90,544 | 90,451 | 81,457 | 8,122 | 9,349 |
| Other Income | 92,627 | 105,464 | 101,222 | 160,328 | 10,387 |
| Pre-tax Income | -379,601 | -460,068 | -333,965 | -257,985 | -29,148 |
| Income Tax | 1,786 | -6,171 | 32,321 | 11,737 | -551 |
| Net Income Continuous | -381,387 | -453,897 | -366,286 | -269,722 | -28,597 |
| Net Income | $-381,387 | $-453,897 | $-366,286 | $-269,722 | $-28,597 |
| EPS Basic Total Ops | -2.38 | -3.04 | -2.56 | -1.90 | -0.20 |
| EPS Basic Continuous Ops | -2.38 | -3.04 | -2.56 | -1.90 | -0.20 |
| EPS Diluted Total Ops | -2.38 | -3.04 | -2.56 | -1.90 | -0.20 |
| EPS Diluted Continuous Ops | -2.38 | -3.04 | -2.56 | -1.90 | -0.20 |
| EPS Diluted Before Non-Recurring Items | -2.38 | -3.04 | -2.56 | -1.90 | -0.20 |
| EBITDA(a) | $-375,817 | $-484,134 | $-353,787 | $-375,324 | $12,108 |