Ionis Pharmaceuticals (IONS)
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Fiscal Year End Date: 12/31
(Values in U.S. thousands)
| 12-2025 | 09-2025 | 06-2025 | 03-2025 | 12-2024 | |
| Cash Flows From Operating Activities | |||||
| Net Income | -381,387 | -151,993 | -23,387 | -146,938 | -453,897 |
| Depreciation Amortization | 5,867 | 2,230 | 1,161 | -69 | -9,053 |
| Accounts receivable | 26,129 | 67,580 | 39,608 | 52,481 | 5,590 |
| Accounts payable and accrued liabilities | -15,360 | -29,116 | -20,309 | -25,968 | 15,990 |
| Other Working Capital | -51,215 | -75,071 | -69,658 | -41,175 | -209,390 |
| Other Operating Activity | 147,383 | 55,496 | 73,148 | 10,894 | 149,813 |
| Operating Cash Flow | $-268,583 | $-130,874 | $563 | $-150,775 | $-500,947 |
| Cash Flows From Investing Activities | |||||
| Change In Deposits | -220,692 | 176,156 | 77,888 | 183,687 | -83,686 |
| PPE Investments | -51,444 | -30,152 | -24,882 | -12,577 | -45,280 |
| Purchase Sale Intangibles | -5,640 | -4,275 | -2,615 | -651 | -5,061 |
| Other Investing Activity | -5,640 | -4,275 | -2,615 | -651 | -5,061 |
| Investing Cash Flow | $-277,776 | $141,729 | $50,391 | $170,459 | $-134,027 |
| Cash Flows From Financing Activities | |||||
| Debt Issued | 770,000 | N/A | -82 | N/A | N/A |
| Debt Repayment | -286,764 | -123 | N/A | -42 | -44,671 |
| Common Stock Issued | 192,604 | 84,787 | 3,528 | 2,241 | 522,729 |
| Financing Cash Flow | $675,840 | $84,664 | $3,446 | $2,199 | $478,058 |
| Exchange Rate Effect | 702 | 745 | 827 | 232 | -273 |
| Beginning Cash Position | 242,077 | 242,077 | 242,077 | 242,077 | 399,266 |
| End Cash Position | 372,260 | 338,341 | 297,304 | 264,192 | 242,077 |
| Net Cash Flow | $130,183 | $96,264 | $55,227 | $22,115 | $-157,189 |
| Free Cash Flow | |||||
| Operating Cash Flow | -268,583 | -130,874 | 563 | -150,775 | -500,947 |
| Capital Expenditure | -51,444 | -30,152 | -24,882 | -12,577 | -45,280 |
| Free Cash Flow | -320,027 | -161,026 | -24,319 | -163,352 | -546,227 |