Ionis Pharmaceuticals (IONS)
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Fiscal Year End Date: 12/31
| 12-2004 | 12-2003 | 12-2002 | 12-2001 | 12-2000 | |
| Sales | 42,624 | 49,990 | 80,179 | 53,273 | 37,255 |
| Gross Profit | 42,624 | 49,990 | 80,179 | 53,273 | 37,255 |
| Operating Expenses | 160,477 | 128,968 | 130,992 | 99,375 | 67,880 |
| Operating Income | -117,853 | -78,978 | -50,813 | -46,102 | -30,625 |
| Interest Expense | 22,592 | 18,680 | 16,562 | 15,248 | 13,160 |
| Other Income | -2,058 | 2,662 | -4,867 | -12,482 | -9,700 |
| Pre-tax Income | -142,503 | -94,996 | -72,242 | -73,832 | -53,485 |
| Net Income Continuous | -142,503 | -94,996 | -72,242 | -73,832 | -53,485 |
| Net Income | $-142,503 | $-94,996 | $-72,242 | $-73,832 | $-53,485 |
| EPS Basic Total Ops | -2.52 | -1.73 | -1.35 | -1.70 | -1.48 |
| EPS Basic Continuous Ops | -2.52 | -1.71 | -1.33 | -1.67 | -1.44 |
| EPS Diluted Total Ops | -2.52 | -1.73 | -1.35 | -1.70 | -1.48 |
| EPS Diluted Continuous Ops | -2.52 | -1.71 | -1.33 | -1.67 | -1.44 |
| EBITDA(a) | $-105,683 | $-66,725 | $-41,389 | $-39,135 | $-25,090 |