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Zentalis Pharmaceuticals Inc (ZNTL)

Zentalis Pharmaceuticals Inc (ZNTL)
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Fundamentals

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  • Market Capitalization, $K 304,676
  • Shares Outstanding, K 71,186
  • Annual Sales, $ 0 K
  • Annual Income, $ -137,060 K
  • EBIT $ -145 M
  • EBITDA $ -147 M
  • 60-Month Beta 1.99
  • Price/Sales N/A
  • Price/Cash Flow N/A
  • Price/Book 1.43

Options Overview Details

View History
  • Implied Volatility 289.07% (-18.33%)
  • Historical Volatility 197.49%
  • IV Percentile 72%
  • IV Rank 33.12%
  • IV High 664.07% on 10/14/25
  • IV Low 103.37% on 01/16/26
  • Expected Move (DTE 34) 1.61 (39.28%)
  • Put/Call Vol Ratio 3.00
  • Today's Volume 4
  • Volume Avg (30-Day) 192
  • Put/Call OI Ratio 0.07
  • Today's Open Interest 8,069
  • Open Int (30-Day) 7,973
  • Expected Range 2.48 to 5.70

Analyst Rating / Earnings Estimates

Current Rating
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Moderate Buy
Based on 10 analysts offering recommendations.
Earnings Estimates - Current Qtr 06/30/26
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  • Average Estimate $-0.46
  • Number of Estimates 5
  • High Estimate $-0.35
  • Low Estimate $-0.54
  • Prior Year $-0.37
  • Growth Rate Est. (year over year) -24.32%

Price Performance

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Period Period Low Period High Performance
1-Month
3.75 +9.07%
on 04/24/26
5.57 -26.64%
on 04/15/26
-1.11 (-21.35%)
since 04/14/26
3-Month
2.07 +97.58%
on 03/30/26
6.95 -41.15%
on 04/10/26
+1.70 (+71.13%)
since 02/13/26
52-Week
1.13 +261.95%
on 07/01/25
6.95 -41.15%
on 04/10/26
+2.90 (+243.70%)
since 05/14/25

Most Recent Stories

More News
Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences

SAN DIEGO, May 13, 2026 (GLOBE NEWSWIRE) -- Zentalis ®  Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhibitor...

ZNTL : 4.09 (-4.44%)
Zentalis Pharmaceuticals Reports First Quarter 2026 Financial Results and Clinical Progress

400mg QD 5:2 selected as azenosertib monotherapy pivotal study dose based on favorable benefit-risk profile in DENALI Part 2a, supporting advancement in registration-intended trials DENALI Phase 2 trial...

ZNTL : 4.09 (-4.44%)
A Breakout Year for WEE1? Oppenheimer Sees 6x Upside in This Under-the-Radar Biotech

Analysts have initiated bullish coverage of Aprea Therapeutics with price targets up to 6x current levels, citing the superior safety profile and $700M peak sales potential of its WEE1 inhibitor program...

AZN : 184.96 (-1.47%)
ZNTL : 4.09 (-4.44%)
ACRV : 1.9200 (unch)
SDGR : 12.62 (-1.02%)
APRE : 0.9410 (+6.93%)
Zentalis Pharmaceuticals Announces First Patient Dosed in ASPENOVA Phase 3 Trial of Azenosertib in Patients with Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

Global Phase 3, randomized, controlled trial comparing azenosertib to standard-of-care chemotherapy now enrolling ASPENOVA designed as confirmatory study to support DENALI Phase 2 accelerated approval...

ZNTL : 4.09 (-4.44%)
Zentalis Pharmaceuticals Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

SAN DIEGO, May 01, 2026 (GLOBE NEWSWIRE) -- Zentalis ®  Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhibitor...

ZNTL : 4.09 (-4.44%)
Zentalis Pharmaceuticals Announces Abstract Acceptance at ASCO 2026 Featuring Azenosertib in Combination with Paclitaxel for Platinum-Resistant Ovarian Cancer

SAN DIEGO, April 21, 2026 (GLOBE NEWSWIRE) -- Zentalis ® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1...

ZNTL : 4.09 (-4.44%)
Zentalis Surges 20% on WEE1 Inhibitor Dose Selection—But Is Aprea the Real Winner in This Space?

While Zentalis’ dose selection marks a significant clinical milestone, the underlying data suggests that Aprea’s APR-1051 may offer a superior therapeutic profile by maintaining daily dosing

ZNTL : 4.09 (-4.44%)
Zentalis Pharmaceuticals To Present Azenosertib Preclinical Data in Triple-Negative Breast Cancer and Real-World Analysis of Unmet Need in Cyclin E1-Positive Ovarian Cancer at AACR 2026

Preclinical data show encouraging activity of azenosertib combinations in ADC-resistant TNBC, supporting the potential for pipeline expansion beyond ovarian cancer Real-world data demonstrate Cyclin...

ZNTL : 4.09 (-4.44%)
Aprea Therapeutics Showcases Emerging Clinical Data for WEE1 Inhibitor APR-1051

Aprea Therapeutics (APRE) recently showcased positive preliminary Phase 1 data for its next-generation WEE1 inhibitor, APR-1051, highlighting early tumor reduction in biomarker-defined cancer

AZN : 184.96 (-1.47%)
ZNTL : 4.09 (-4.44%)
MRK : 113.41 (-0.04%)
APRE : 0.9410 (+6.93%)
Zentalis Pharmaceuticals Announces 400mg QD 5:2 Azenosertib Monotherapy as the Pivotal Study Dose in Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

Planned interim analysis from DENALI Part 2a showed a clearly differentiated response rate at 400mg QD 5:2 over 300mg QD 5:2 and comparable safety profiles between the two dose groups Azenosertib therapeutic...

ZNTL : 4.09 (-4.44%)

Business Summary

Zentalis Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. It is focused on discovering and developing small molecule therapeutics targeting cancers. The company's lead programs consist of ZN-c5, an oral selective estrogen receptor degrader for estrogen-receptor-positive, HER2-negative...

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Key Turning Points

3rd Resistance Point 4.82
2nd Resistance Point 4.61
1st Resistance Point 4.35
Last Price 4.09
1st Support Level 3.87
2nd Support Level 3.66
3rd Support Level 3.40

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52-Week High 6.95
Fibonacci 61.8% 4.73
Last Price 4.09
Fibonacci 50% 4.04
Fibonacci 38.2% 3.35
52-Week Low 1.13

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