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Alnylam Pharmaceuticals (ALNY)

Alnylam Pharmaceuticals (ALNY)
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Alnylam Pharmaceuticals Inc. is a development-stage biopharmaceutical company focused on the development of novel therapeutics based on RNA interference. The company's pipeline of experimental RNAi therapeutics is focused across three strategic therapeutic areas - genetic medicines, cardio-metabolic disease and hepatic infectious disease. The company's lead drug-Onpattro received regulatory approvals in the United States and Europe for the treatment of hereditary transthyretin-mediated amyloidosis in adults. The FDA approved Givlaari for acute hepatic porphyria. The FDA approved Oxlumo injection for subcutaneous use, for the treatment of primary hyperoxaluria type 1 to lower urinary oxalate levels in pediatric and adult patients. Moreover, the company is evaluating inclisiran for hypercholesterolemia in partnership with The Medicines Company acquired by Novartis. The FDA approved Leqvio to reduce low-density lipoprotein cholesterol with two doses a year..

Fiscal Year End Date: 12/31

(Values in U.S. Thousands) Dec, 2025 Dec, 2024 Dec, 2023 Dec, 2022 Dec, 2021
Sales 3,713,940 2,248,240 1,828,290 1,037,420 844,290
Sales Growth +65.19% +22.97% +76.23% +22.87% +71.31%
Net Income 313,750 -278,160 -440,240 -1,131,160 -852,820
Net Income Growth +212.79% +36.82% +61.08% -32.64% +0.64%
(Values in U.S. Thousands) Dec, 2025 Dec, 2024 Dec, 2023 Dec, 2022 Dec, 2021
Total Assets 4,966,330 4,239,980 3,829,880 3,546,360 3,643,300
Total Assets Growth +17.13% +10.71% +7.99% -2.66% +6.93%
Total Liabilities 4,177,160 4,172,900 4,050,520 3,704,580 3,055,100
Total Liabilities Growth +0.10% +3.02% +9.34% +21.26% +27.79%
(Values in U.S. Thousands) Dec, 2025 Dec, 2024 Dec, 2023 Dec, 2022 Dec, 2021
Operating Cash Flow 524,080 -8,310 104,160 -541,270 -641,690
Operating Cash Flow Growth +6,406.62% -107.98% +119.24% +15.65% -4.35%
Net Cash Flow 690,160 153,770 -53,670 46,400 323,110
Change in Net Cash Flow +348.83% +386.51% -215.67% -85.64% +738.81%
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