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Stoke Therapeutics Inc (STOK)

Stoke Therapeutics Inc (STOK)
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Market News and Commentary

Stoke Therapeutics Prepares to Defend Its Pipeline Narrative, But Zorevunersen Data Timing Looms Large

Stoke Therapeutics (STOK) reports second-quarter 2026 earnings after market close on August 3, with analysts expecting a loss of $0.82 per share. The central question for investors is whether the clinical-stage biotech can demonstrate progress on its lead candidate zorevunersen for Dravet syndrome while managing cash burn, as the company navigates a critical period between Phase III data readouts and potential commercialization.

Stoke Therapeutics is a clinical-stage biotechnology company focused on developing antisense oligonucleotide (ASO) medicines to treat severe genetic diseases by upregulating protein expression. The company's lead candidate, zorevunersen, targets Dravet syndrome, a rare and severe form of epilepsy, with additional programs...

Fundamentals

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  • Market Capitalization, $K 1,797,459
  • Shares Outstanding, K 62,282
  • Annual Sales, $ 184,420 K
  • Annual Income, $ -6,890 K
  • EBIT $ -185 M
  • EBITDA $ -185 M
  • 60-Month Beta 1.17
  • Price/Sales 10.15
  • Price/Cash Flow N/A
  • Price/Book 4.74

Options Overview Details

View History
  • Implied Volatility 70.99% (+11.18%)
  • Historical Volatility 39.67%
  • IV Percentile 8%
  • IV Rank 24.69%
  • IV High 144.29% on 08/11/25
  • IV Low 46.96% on 05/21/26
  • Expected Move (DTE 20) 3.32 (11.49%)
  • Put/Call Vol Ratio 0.00
  • Today's Volume 10
  • Volume Avg (30-Day) 163
  • Put/Call OI Ratio 5.09
  • Today's Open Interest 3,369
  • Open Int (30-Day) 1,777
  • Expected Range 25.55 to 32.18

Analyst Rating / Earnings Estimates

Current Rating
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Strong Buy
Based on 14 analysts offering recommendations.
Earnings Estimates - Current Qtr 06/30/26
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  • Average Estimate $-0.82
  • Number of Estimates 2
  • High Estimate $-0.78
  • Low Estimate $-0.86
  • Prior Year $-0.40
  • Growth Rate Est. (year over year) -105.00%

Price Performance

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Period Period Low Period High Performance
1-Month
27.24 +5.97%
on 07/21/26
33.72 -14.41%
on 07/07/26
-3.86 (-11.80%)
since 06/30/26
3-Month
27.24 +5.97%
on 07/21/26
35.24 -18.10%
on 05/05/26
-3.86 (-11.80%)
since 04/30/26
52-Week
12.40 +132.65%
on 08/01/25
40.22 -28.24%
on 03/10/26
+15.99 (+124.24%)
since 07/30/25

Most Recent Stories

More News
Stoke Therapeutics Prepares to Defend Its Pipeline Narrative, But Zorevunersen Data Timing Looms Large

Barchart Research What to Expect from STOK Earnings STOK Generated July 31, 2026 Current Price $28.86 EPS Estimate $$-0.82 Consensus Rating Strong Buy Average Move 6.33% Stoke Therapeutics Prepares to...

STOK : 28.86 (-3.93%)
Stoke Therapeutics to Host Webcast and Conference Call to Discuss Second Quarter 2026 Business and Financial Updates

Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational medicine,...

STOK : 28.86 (-3.93%)
BIIB : 202.95 (-2.40%)
Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational...

STOK : 28.86 (-3.93%)
Stoke Therapeutics Appoints Thomas McCauley, Ph.D., as Chief Scientific Officer

–Dr. McCauley brings more than 25 years of experience building high-performing R&D organizations and translating early scientific discoveries into new medicines for people with severe diseases–

STOK : 28.86 (-3.93%)
BIIB : 202.95 (-2.40%)
Stoke Therapeutics Announces Completion of Enrollment of 162 Patients Into the Phase 3 EMPEROR Study of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome

—Company plans to initiate a rolling U.S. NDA submission to the FDA in the first quarter of 2027— —Phase 3 data readout anticipated in the third quarter of 2027...

STOK : 28.86 (-3.93%)
BIIB : 202.95 (-2.40%)
Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational...

STOK : 28.86 (-3.93%)
Stoke Therapeutics to Present at Upcoming Investor Conferences in June

Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational...

STOK : 28.86 (-3.93%)
BIIB : 202.95 (-2.40%)
Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational...

STOK : 28.86 (-3.93%)
Stoke Therapeutics Q1 Earnings Call Highlights

Stoke Therapeutics (NASDAQ:STOK) said its lead investigational therapy zorevunersen continued to show durable seizure reductions and improvements in measures of cognition and behavior in four-year open-label...

STOK : 28.86 (-3.93%)
Stoke Therapeutics Announces First Quarter 2026 Financial Results and Provides Business Updates

– New 4-year longitudinal data from the Phase 1/2a open-label extension (OLE) studies provide additional support for the disease-modifying potential of zorevunersen, an investigational medicine for the...

STOK : 28.86 (-3.93%)
BIIB : 202.95 (-2.40%)

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 88% Sell with a Strongest short term outlook on maintaining the current direction.

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Business Summary

Stoke Therapeutics Inc. is a biopharmaceutical company. It develops antisense oligonucleotide medicines to treat genetic diseases. The company's product candidate consists of STK-001 which is to treat Dravet syndrome, a severe and progressive genetic epilepsy. Stoke Therapeutics Inc. is based in Bedford,...

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Key Turning Points

3rd Resistance Point 30.97
2nd Resistance Point 30.49
1st Resistance Point 29.67
Last Price 28.86
1st Support Level 28.37
2nd Support Level 27.89
3rd Support Level 27.07

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52-Week High 40.22
Fibonacci 61.8% 29.59
Last Price 28.86
Fibonacci 50% 26.31
Fibonacci 38.2% 23.03
52-Week Low 12.40

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