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Sionna Therapeutics Inc (SION)

Sionna Therapeutics Inc (SION)
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Fundamentals

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  • Market Capitalization, $K 1,890,931
  • Shares Outstanding, K 44,629
  • Annual Sales, $ 0 K
  • Annual Income, $ -61,690 K
  • EBIT $ -84 M
  • EBITDA $ -86 M
  • 60-Month Beta N/A
  • Price/Sales N/A
  • Price/Cash Flow N/A
  • Price/Book 5.81

Analyst Rating / Earnings Estimates

Current Rating
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Moderate Buy
Based on 8 analysts offering recommendations.
Earnings Estimates - Current Qtr 12/31/25
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  • Average Estimate -0.61
  • Number of Estimates 3
  • High Estimate -0.47
  • Low Estimate -0.71
  • Prior Year -3.38
  • Growth Rate Est. (year over year) +81.95%

Price Performance

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Period Period Low Period High Performance
1-Month
35.42 +19.62%
on 12/01/25
45.00 -5.84%
on 12/19/25
+3.96 (+10.31%)
since 11/19/25
3-Month
22.79 +85.91%
on 09/22/25
45.00 -5.84%
on 12/19/25
+19.23 (+83.10%)
since 09/19/25

Most Recent Stories

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Stocks Retreat as Bond Yields Rise

The S&P 500 Index ($SPX ) (SPY ) on Monday closed down by -0.53%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.90%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.36%....

MSTR : 164.82 (+4.16%)
MPC : 168.32 (+0.12%)
GLXY : 24.00 (+6.62%)
LVS : 66.95 (-0.01%)
WYNN : 127.94 (+1.13%)
$IUXX : 25,346.18 (+1.31%)
COIN : 245.12 (+2.47%)
ZNH26 : 112-160s (-0.22%)
SHOP : 169.57 (+1.66%)
SION : 42.37 (-4.16%)
ESH26 : 6,887.25s (+0.83%)
FANG : 148.13 (+0.77%)
Stocks Fall as Rising Bond Yields Spark Risk-Off Sentiment

The S&P 500 Index ($SPX ) (SPY ) today is down by -0.28%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -0.48%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -0.29%. December E-mini...

MSTR : 164.82 (+4.16%)
MPC : 168.32 (+0.12%)
CVX : 147.75 (+0.04%)
GLXY : 24.00 (+6.62%)
LVS : 66.95 (-0.01%)
WYNN : 127.94 (+1.13%)
$IUXX : 25,346.18 (+1.31%)
COIN : 245.12 (+2.47%)
ZNH26 : 112-160s (-0.22%)
SHOP : 169.57 (+1.66%)
OXY : 39.62 (-0.28%)
SION : 42.37 (-4.16%)
Stocks Pressured by Higher Bond Yields

The S&P 500 Index ($SPX ) (SPY ) today is down by -0.59%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -0.40%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -0.97%. December E-mini...

MSTR : 164.82 (+4.16%)
MPC : 168.32 (+0.12%)
CVX : 147.75 (+0.04%)
GLXY : 24.00 (+6.62%)
LVS : 66.95 (-0.01%)
WYNN : 127.94 (+1.13%)
$IUXX : 25,346.18 (+1.31%)
COIN : 245.12 (+2.47%)
ZNH26 : 112-160s (-0.22%)
SHOP : 169.57 (+1.66%)
OXY : 39.62 (-0.28%)
SION : 42.37 (-4.16%)
Sionna Therapeutics to Participate in Upcoming December Investor Conferences

WALTHAM, Mass., Nov. 24, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for...

SION : 42.37 (-4.16%)
Sionna Therapeutics Reports Third Quarter 2025 Financial Results

Initiated PreciSION CF Phase 2a proof-of-concept trial evaluating NBD1 stabilizer SION-719 as an add-on to standard of care in participants with cystic fibrosis Successfully completed drug-drug interaction...

SION : 42.37 (-4.16%)
Sionna Therapeutics to Participate in Upcoming November Investor Conferences

WALTHAM, Mass., Nov. 04, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for...

SION : 42.37 (-4.16%)
Sionna Therapeutics Announces Presentation of SION-719 and SION-451 Phase 1 Data and Poster of New Preclinical Data on the Impact of NBD1 Stabilizers on F508del-CFTR Half-Life at the 2025 North American Cystic Fibrosis Conference

Phase 1 data of first-in-class NBD1 stabilizers, SION-719 and SION-451, demonstrated they were generally well tolerated and exceeded desired pharmacokinetic targets New preclinical data show that...

SION : 42.37 (-4.16%)
Sionna Therapeutics Announces Initiation of PreciSION CF Phase 2a Trial Evaluating NBD1 Stabilizer, SION-719, When Added to Standard of Care in Participants with Cystic Fibrosis

SION-719 is the first NBD1 stabilizer being evaluated in people living with cystic fibrosis Topline data expected in mid-2026 WALTHAM, Mass., Oct. 21, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics,...

SION : 42.37 (-4.16%)
Sionna Therapeutics, Inc. (SION) Gets a Buy from Raymond James

Raymond James analyst maintained a Buy rating on Sionna Therapeutics, Inc. today and set a price target of $45.00. The company’s shares closed yesterday at $30.91.Elevate Your Investing Strategy: Take...

SION : 42.37 (-4.16%)
Sionna Therapeutics to Present Data at the 2025 North American Cystic Fibrosis Conference

WALTHAM, Mass., Oct. 01, 2025 (GLOBE NEWSWIRE) -- Sionna Therapeutics, Inc. (Nasdaq: SION), a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for...

SION : 42.37 (-4.16%)

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 100% Buy with a Average short term outlook on maintaining the current direction.

Long term indicators fully support a continuation of the trend.

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Business Summary

Sionna Therapeutics Inc. is a clinical-stage biopharmaceutical company by developing novel medicines that normalize the function of the CFTR protein. Sionna Therapeutics Inc. is based in BOSTON.

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Key Turning Points

3rd Resistance Point 46.93
2nd Resistance Point 45.96
1st Resistance Point 44.17
Last Price 42.37
1st Support Level 41.41
2nd Support Level 40.44
3rd Support Level 38.65

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52-Week High 45.00
Last Price 42.37
Fibonacci 61.8% 30.58
Fibonacci 50% 26.13
Fibonacci 38.2% 21.67
52-Week Low 7.26

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