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Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals (IONS)
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Fundamentals

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  • Market Capitalization, $K 12,512,061
  • Shares Outstanding, K 165,263
  • Annual Sales, $ 943,710 K
  • Annual Income, $ -381,390 K
  • EBIT $ -352 M
  • EBITDA $ -346 M
  • 60-Month Beta 0.38
  • Price/Sales 13.31
  • Price/Cash Flow N/A
  • Price/Book 25.57

Options Overview Details

View History
  • Implied Volatility 36.38% (+6.42%)
  • Historical Volatility 24.23%
  • IV Percentile 5%
  • IV Rank 14.51%
  • IV High 74.24% on 08/20/25
  • IV Low 29.96% on 05/07/26
  • Expected Move (DTE 5) 2.45 (3.23%)
  • Put/Call Vol Ratio 0.06
  • Today's Volume 426
  • Volume Avg (30-Day) 858
  • Put/Call OI Ratio 0.68
  • Today's Open Interest 50,197
  • Open Int (30-Day) 44,610
  • Expected Range 73.26 to 78.16

Analyst Rating / Earnings Estimates

Current Rating
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Strong Buy
Based on 22 analysts offering recommendations.
Earnings Estimates - Current Qtr 06/30/26
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  • Average Estimate $-1.08
  • Number of Estimates 8
  • High Estimate $-0.82
  • Low Estimate $-1.34
  • Prior Year $0.70
  • Growth Rate Est. (year over year) -254.29%

Price Performance

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Period Period Low Period High Performance
1-Month
71.18 +6.37%
on 04/28/26
77.76 -2.64%
on 04/30/26
+0.73 (+0.97%)
since 04/08/26
3-Month
68.90 +9.88%
on 03/24/26
86.49 -12.46%
on 02/09/26
-10.79 (-12.47%)
since 02/06/26
52-Week
32.00 +136.59%
on 05/29/25
86.74 -12.72%
on 02/05/26
+42.96 (+131.18%)
since 05/08/25

Most Recent Stories

More News
Ionis to host 2026 virtual Annual Meeting of Stockholders

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will conduct its 2026 virtual Annual Meeting of Stockholders followed by a general corporate update on Thursday, June 4, 2026....

IONS : 75.71 (-0.41%)
Ionis to present at upcoming investor conferences

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Bank of America Securities 2026...

IONS : 75.71 (-0.41%)
Ionis Pharmaceuticals: Q1 Earnings Snapshot

Ionis Pharmaceuticals: Q1 Earnings Snapshot

IONS : 75.71 (-0.41%)
Ionis reports first quarter 2026 financial results and highlights progress on key programs

- TRYNGOLZA ® (olezarsen) showed increasing demand in FCS driven by strong launch execution – - Olezarsen sNDA accepted by the FDA for Priority...

IONS : 75.71 (-0.41%)
Ionis Pharmaceuticals Approaches Its Earnings Call With Pipeline Momentum and Profitability Questions in Balance

Barchart Research What to Expect from IONS Earnings IONS Generated April 28, 2026 Current Price $71.78 EPS Estimate $$-0.89 Consensus Rating Moderate Buy Average Move 2.90% Ionis Pharmaceuticals Approaches...

IONS : 75.71 (-0.41%)
Ionis partner GSK announces bepirovirsen accepted for Priority Review and granted Breakthrough Therapy Designation by U.S. FDA as a potential first-in-class medicine for chronic hepatitis B

– Regulatory submission supported by Phase 3 B-Well trials demonstrating statistically significant and clinically meaningful functional cure rates in chronic hepatitis B - ...

IONS : 75.71 (-0.41%)
Ionis presents new data from pivotal study of zilganersen in Alexander disease (AxD) at AAN 2026 Annual Meeting

– New data highlight potential treatment benefit across multiple AxD symptom domains, reinforcing zilganersen’s positive impact on people living with this rare, often fatal neurological disease...

IONS : 75.71 (-0.41%)
Ionis to hold first quarter 2026 financial results webcast

Webcast scheduled for Wednesday, April 29 at 8:30 a.m. Eastern Time

IONS : 75.71 (-0.41%)
When Insider Selling Is a Good Thing: 2 Stocks to Watch

Ionis Pharmaceuticals and Waste Management insiders sell in early 2026, creating buying opportunities in their stocks while analysts raise price targets.

WM : 215.37 (-2.75%)
IONS : 75.71 (-0.41%)
Ionis announces zilganersen New Drug Application for Alexander disease (AxD) accepted by FDA for Priority Review

– PDUFA date set for September 22, 2026 –

IONS : 75.71 (-0.41%)

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 16% Buy with a Weakest short term outlook on maintaining the current direction.

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Business Summary

Ionis Pharmaceuticals discovers/develops RNA-targeted therapeutics using its proprietary antisense oligonucleotide technology. Its antisense medicines have been developed/are being developed to treat neurological, cardiovascular and specialty rare diseases.

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Key Turning Points

3rd Resistance Point 79.15
2nd Resistance Point 78.28
1st Resistance Point 76.99
Last Price 75.71
1st Support Level 74.83
2nd Support Level 73.96
3rd Support Level 72.67

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52-Week High 86.74
Last Price 75.71
Fibonacci 61.8% 65.83
Fibonacci 50% 59.37
Fibonacci 38.2% 52.91
52-Week Low 32.00

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