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Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals (IONS)
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Realtime quote and/or trades are not sourced from all markets.

Fundamentals

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  • Market Capitalization, $K 9,055,367
  • Shares Outstanding, K 166,184
  • Annual Sales, $ 943,710 K
  • Annual Income, $ -381,390 K
  • EBIT $ -594 M
  • EBITDA $ -588 M
  • 60-Month Beta 0.41
  • Price/Sales 9.11
  • Price/Cash Flow N/A
  • Price/Book 20.14

Options Overview Details

View History
  • Implied Volatility 47.93% (+0.40%)
  • Historical Volatility 89.48%
  • IV Percentile 59%
  • IV Rank 40.58%
  • IV High 74.24% on 08/20/25
  • IV Low 29.96% on 05/07/26
  • Expected Move (DTE 17) 4.14 (7.60%)
  • Put/Call Vol Ratio 0.25
  • Today's Volume 2,278
  • Volume Avg (30-Day) 6,491
  • Put/Call OI Ratio 0.46
  • Today's Open Interest 92,609
  • Open Int (30-Day) 98,002
  • Expected Range 50.35 to 58.63

Analyst Rating / Earnings Estimates

Current Rating
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Strong Buy
Based on 22 analysts offering recommendations.
Earnings Estimates - Current Qtr 09/30/26
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  • Average Estimate $-1.14
  • Number of Estimates 8
  • High Estimate $-1.02
  • Low Estimate $-1.37
  • Prior Year $-0.80
  • Growth Rate Est. (year over year) -42.50%

Price Performance

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Period Period Low Period High Performance
1-Month
50.01 +8.97%
on 07/22/26
86.74 -37.18%
on 07/08/26
-27.31 (-33.39%)
since 07/02/26
3-Month
50.01 +8.97%
on 07/22/26
86.74 -37.18%
on 07/08/26
-20.79 (-27.62%)
since 05/01/26
52-Week
40.03 +36.12%
on 08/07/25
86.74 -37.18%
on 07/08/26
+11.46 (+26.63%)
since 08/01/25

Most Recent Stories

More News
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Ionis Pharmaceuticals, Inc. - IONS

NEW YORK , July 30, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Ionis Pharmaceuticals, Inc. ("Ionis" or the "Company") (NASDAQ: IONS).  Such investors are...

IONS : 54.49 (+5.25%)
Ionis Pharmaceuticals: Q2 Earnings Snapshot

Ionis Pharmaceuticals: Q2 Earnings Snapshot

IONS : 54.49 (+5.25%)
Ionis announces Dr. Frank Bennett, chief scientific officer, to retire

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that Frank Bennett, Ph.D., executive vice president and chief scientific officer, will retire effective February 2027. “As...

IONS : 54.49 (+5.25%)
Ionis reports second quarter 2026 financial results and highlights progress on key programs

- TRYNGOLZA ® (olezarsen) demonstrating early sHTG launch momentum, underscoring multi-billion-dollar revenue potential in large patient population – ...

IONS : 54.49 (+5.25%)
Ionis Faces Its Easiest Earnings Comparison in Years With Expectations Already Reset

Barchart Research What to Expect from IONS Earnings IONS Generated July 28, 2026 Current Price $55.30 EPS Estimate $$-1.11 Consensus Rating Moderate Buy Average Move 3.03% Ionis Faces Its Easiest Earnings...

IONS : 54.49 (+5.25%)
Ionis Pharmaceuticals, Inc. (IONS) Faces Investor Scrutiny After Surprise Trial Failure Drives Stock Down 23% - HBSS

SAN FRANCISCO , July 23, 2026 /PRNewswire/ -- Investors in Ionis Pharmaceuticals, Inc. ( NASDAQ: IONS ) saw the price of their shares plunge $20.19 (-23%) on July 9, 2026 after the commercial...

IONS : 54.49 (+5.25%)
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Ionis Pharmaceuticals, Inc. - IONS

NEW YORK , July 23, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Ionis Pharmaceuticals, Inc. ("Ionis" or the "Company") (NASDAQ: IONS). Such investors are...

IONS : 54.49 (+5.25%)
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Ionis Pharmaceuticals, Inc. - IONS

NEW YORK , July 16, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Ionis Pharmaceuticals, Inc. ("Ionis" or the "Company") (NASDAQ: IONS). Such investors are...

IONS : 54.49 (+5.25%)
Ionis to hold second quarter 2026 financial results webcast

Webcast scheduled for Wednesday, July 29 at 8:30 a.m. Eastern Time

IONS : 54.49 (+5.25%)
An experimental Alzheimer's drug shows promise targeting a different brain protein, new study shows

An experimental drug might help slow early Alzheimer's disease in a markedly different way than current treatments — by lowering the brain's production of a protein called tau

DNLI : 23.15 (+0.56%)
IONS : 54.49 (+5.25%)
NAMS : 27.49 (-1.08%)
BIIB : 201.82 (-0.56%)

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 100% Sell with a Strengthening short term outlook on maintaining the current direction.

Long term indicators fully support a continuation of the trend.

Relative Strength just crossed above 30%. The market has bounced from oversold territory. Beware of a potential mean reversion.

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Business Summary

Ionis Pharmaceuticals discovers/develops RNA-targeted therapeutics using its proprietary antisense oligonucleotide technology. Its antisense medicines have been developed/are being developed to treat neurological, cardiovascular and specialty rare diseases.

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Key Turning Points

3rd Resistance Point 57.67
2nd Resistance Point 56.11
1st Resistance Point 55.30
Last Price 54.49
1st Support Level 52.92
2nd Support Level 51.36
3rd Support Level 50.55

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52-Week High 86.74
Fibonacci 61.8% 68.90
Fibonacci 50% 63.38
Fibonacci 38.2% 57.87
Last Price 54.49
52-Week Low 40.03

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