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Ionis Pharmaceuticals (IONS)

Ionis Pharmaceuticals (IONS)
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Fundamentals

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  • Market Capitalization, $K 11,918,604
  • Shares Outstanding, K 165,192
  • Annual Sales, $ 943,710 K
  • Annual Income, $ -381,390 K
  • EBIT $ -382 M
  • EBITDA $ -376 M
  • 60-Month Beta 0.31
  • Price/Sales 12.99
  • Price/Cash Flow N/A
  • Price/Book 24.59

Options Overview Details

View History
  • Implied Volatility 42.95% (-5.08%)
  • Historical Volatility 34.40%
  • IV Percentile 19%
  • IV Rank 13.84%
  • IV High 86.76% on 04/09/25
  • IV Low 35.92% on 09/08/25
  • Expected Move (DTE 17) 4.80 (6.62%)
  • Put/Call Vol Ratio 0.22
  • Today's Volume 60
  • Volume Avg (30-Day) 1,501
  • Put/Call OI Ratio 0.99
  • Today's Open Interest 40,555
  • Open Int (30-Day) 38,635
  • Expected Range 67.72 to 77.32

Analyst Rating / Earnings Estimates

Current Rating
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Moderate Buy
Based on 20 analysts offering recommendations.
Earnings Estimates - Current Qtr 03/31/26
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  • Average Estimate -0.81
  • Number of Estimates 7
  • High Estimate -0.39
  • Low Estimate -1.21
  • Prior Year -0.93
  • Growth Rate Est. (year over year) +12.90%

Price Performance

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Period Period Low Period High Performance
1-Month
68.90 +5.25%
on 03/24/26
82.75 -12.36%
on 03/02/26
-8.63 (-10.63%)
since 02/27/26
3-Month
68.90 +5.25%
on 03/24/26
86.74 -16.39%
on 02/05/26
-7.41 (-9.27%)
since 12/26/25
52-Week
23.95 +202.80%
on 04/09/25
86.74 -16.39%
on 02/05/26
+41.37 (+132.81%)
since 03/28/25

Most Recent Stories

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When Insider Selling Is a Good Thing: 2 Stocks to Watch

Ionis Pharmaceuticals and Waste Management insiders sell in early 2026, creating buying opportunities in their stocks while analysts raise price targets.

WM : 229.96 (+2.18%)
IONS : 72.52 (+0.51%)
Ionis announces zilganersen New Drug Application for Alexander disease (AxD) accepted by FDA for Priority Review

– PDUFA date set for September 22, 2026 –

IONS : 72.52 (+0.51%)
Ionis announces changes to Board of Directors

– Lynne Parshall and Joseph Wender to retire at end of term in June 2026 and Peter Reikes to join Ionis Board –

IONS : 72.52 (+0.51%)
Ionis to present new data supporting DAWNZERA™ (donidalorsen) in hereditary angioedema at 2026 AAAAI Annual Meeting

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced new data to be presented for DAWNZERA™ (donidalorsen), the first and only RNA-targeted medicine for hereditary angioedema (HAE), including...

IONS : 72.52 (+0.51%)
Olezarsen sNDA accepted by the FDA for Priority Review for the treatment of severe hypertriglyceridemia (sHTG)

– PDUFA date set for June 30, 2026 –

IONS : 72.52 (+0.51%)
Ionis Pharmaceuticals: Q4 Earnings Snapshot

Ionis Pharmaceuticals: Q4 Earnings Snapshot

IONS : 72.52 (+0.51%)
Ionis reports fourth quarter and full year 2025 financial results and highlights progress on key programs

- TRYNGOLZA ® generated $108 million in net product sales in 2025, the first year of launch – - Olezarsen sHTG launch preparations on track,...

IONS : 72.52 (+0.51%)
Ionis to present at upcoming investor conferences

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Oppenheimer 36 ...

IONS : 72.52 (+0.51%)
Ionis updates time for fourth quarter and full year 2025 financial results webcast

Webcast scheduled for Wednesday, February 25 at 8:30 a.m. Eastern Time

IONS : 72.52 (+0.51%)
Ionis to hold fourth quarter and full year 2025 financial results webcast

Webcast scheduled for Wednesday, February 25 at 11:30 a.m. Eastern Time

IONS : 72.52 (+0.51%)

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 8% Sell with a Weakening short term outlook on maintaining the current direction.

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Business Summary

Ionis Pharmaceuticals discovers/develops RNA-targeted therapeutics using its proprietary antisense oligonucleotide technology. Its antisense medicines have been developed/are being developed to treat neurological, cardiovascular and specialty rare diseases.

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Key Turning Points

3rd Resistance Point 75.06
2nd Resistance Point 74.13
1st Resistance Point 73.33
Last Price 72.52
1st Support Level 71.60
2nd Support Level 70.67
3rd Support Level 69.87

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52-Week High 86.74
Last Price 72.52
Fibonacci 61.8% 62.75
Fibonacci 50% 55.35
Fibonacci 38.2% 47.94
52-Week Low 23.95

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