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Denali Therapeutics Inc (DNLI)

Denali Therapeutics Inc (DNLI)
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Fundamentals

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  • Market Capitalization, $K 2,927,374
  • Shares Outstanding, K 146,662
  • Annual Sales, $ 0 K
  • Annual Income, $ -422,770 K
  • EBIT $ -548 M
  • EBITDA $ -575 M
  • 60-Month Beta 1.11
  • Price/Sales N/A
  • Price/Cash Flow N/A
  • Price/Book 3.17

Options Overview Details

View History
  • Implied Volatility 100.05% (+11.55%)
  • Historical Volatility 61.02%
  • IV Percentile 83%
  • IV Rank 49.28%
  • IV High 155.38% on 11/13/25
  • IV Low 46.31% on 01/21/25
  • Expected Move (DTE 13) 1.39 (6.94%)
  • Put/Call Vol Ratio 0.00
  • Today's Volume 35
  • Volume Avg (30-Day) 50
  • Put/Call OI Ratio 0.51
  • Today's Open Interest 2,147
  • Open Int (30-Day) 2,204
  • Expected Range 18.57 to 21.35

Analyst Rating / Earnings Estimates

Current Rating
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Strong Buy
Based on 18 analysts offering recommendations.
Earnings Estimates - Current Qtr 12/31/25
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  • Average Estimate -0.76
  • Number of Estimates 12
  • High Estimate -0.62
  • Low Estimate -0.93
  • Prior Year -0.67
  • Growth Rate Est. (year over year) -13.43%

Price Performance

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Period Period Low Period High Performance
1-Month
13.75 +45.16%
on 11/07/25
20.61 -3.15%
on 12/05/25
+5.07 (+34.05%)
since 11/05/25
3-Month
12.58 +58.66%
on 09/22/25
20.61 -3.15%
on 12/05/25
+4.53 (+29.36%)
since 09/05/25
52-Week
10.57 +88.84%
on 04/07/25
26.18 -23.76%
on 12/09/24
-3.36 (-14.41%)
since 12/05/24

Most Recent Stories

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Royalty Pharma and Denali Therapeutics Announce $275 Million Royalty Funding Agreement

NEW YORK and SOUTH SAN FRANCISCO, Calif., Dec. 04, 2025 (GLOBE NEWSWIRE) -- Royalty Pharma plc (Nasdaq: RPRX) and Denali Therapeutics, Inc. (Nasdaq: DNLI) today announced a $275 million synthetic royalty...

RPRX : 39.73 (+1.48%)
DNLI : 19.96 (-0.75%)
Denali Therapeutics and Royalty Pharma Announce $275 Million Royalty Funding Agreement

SOUTH SAN FRANCISCO, Calif. and NEW YORK, Dec. 04, 2025 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (Nasdaq: DNLI) and Royalty Pharma plc (Nasdaq: RPRX) today announced a $275 million synthetic royalty...

RPRX : 39.73 (+1.48%)
DNLI : 19.96 (-0.75%)
Denali Therapeutics Reports Third Quarter 2025 Financial Results and Business Highlights

Tividenofusp alfa BLA review process for accelerated approval for MPS II continues with productive engagement with the FDA; commercial launch preparations on track DNL126 Phase 1/2 study enrollment completed,...

DNLI : 19.96 (-0.75%)
Denali Therapeutics Announces Board and Executive Leadership Updates

SOUTH SAN FRANCISCO, Calif., Nov. 06, 2025 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (NASDAQ: DNLI) today announced updates to its Board of Directors and executive leadership team. Tim Van Hauwermeiren...

DNLI : 19.96 (-0.75%)
Longevity Biotech Surges as $72.6B Market Forecast Sparks Investment Rush

Issued on behalf of Avant Technologies Inc. VANCOUVER – Baystreet.ca News Commentary – The longevity and cell therapy sector has captured Wall Street's attention as market projections hit $72.6...

AUTL : 1.5500 (-1.27%)
AVAI : 0.2875 (-2.58%)
DNLI : 19.96 (-0.75%)
EDIT : 2.42 (-0.41%)
XNCR : 17.30 (-4.63%)
Oppenheimer Sticks to Its Buy Rating for Denali Therapeutics (DNLI)

In a report released today, Jay Olson from Oppenheimer maintained a Buy rating on Denali Therapeutics, with a price target of $35.00. The company’s shares closed yesterday at $14.98.Elevate Your Investing...

DNLI : 19.96 (-0.75%)
Wedbush Keeps Their Buy Rating on Denali Therapeutics (DNLI)

In a report released today, Laura Chico from Wedbush maintained a Buy rating on Denali Therapeutics, with a price target of $30.00. The company’s shares closed yesterday at $14.98.Elevate Your Investing...

DNLI : 19.96 (-0.75%)
Denali Therapeutics Faces FDA Review Extension

Elevate Your Investing Strategy: Take advantage of TipRanks Premium at 50% off! Unlock powerful investing tools, advanced data, and expert analyst insights to help you invest with confidence. Denali Therapeutics...

DNLI : 19.96 (-0.75%)
Denali Therapeutics (DNLI) Receives a Buy from Stifel Nicolaus

Stifel Nicolaus analyst Paul Matteis maintained a Buy rating on Denali Therapeutics today and set a price target of $37.00. The company’s shares closed yesterday at $14.98.Elevate Your Investing Strategy:...

DNLI : 19.96 (-0.75%)
Denali Therapeutics Announces FDA Review Extension of BLA for Tividenofusp Alfa for the Treatment of MPS II (Hunter Syndrome)

SOUTH SAN FRANCISCO, Calif., Oct. 13, 2025 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (Nasdaq: DNLI) today announced that the U.S. Food and Drug Administration (FDA) has extended its review timeline...

DNLI : 19.96 (-0.75%)

Barchart Technical Opinion

The Barchart Technical Opinion rating is a 100% Buy with a Strongest short term outlook on maintaining the current direction.

Long term indicators fully support a continuation of the trend.

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Business Summary

Denali Therapeutics, a biopharmaceutical company, is developing a wide and innovative portfolio of targeted therapeutic candidates, which are engineered to cross the blood-brain barrier for neurodegenerative diseases. It has 5 clinical-stage programs, a leucine-rich repeat kinase 2 inhibitor program...

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Key Turning Points

3rd Resistance Point 21.07
2nd Resistance Point 20.84
1st Resistance Point 20.40
Last Price 19.96
1st Support Level 19.73
2nd Support Level 19.50
3rd Support Level 19.06

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52-Week High 26.18
Fibonacci 61.8% 20.22
Last Price 19.96
Fibonacci 50% 18.38
Fibonacci 38.2% 16.53
52-Week Low 10.57

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